Hoodia and Diabetes

Is Hoodia good for diabetes?

Is Hoodia bad for diabetes?

Can Hoodia reverse Diabetes?

Which is the true answer?

There are different opinions about the hoodia and diabetes relationship. While some doctors say hoodia is not effective for diabetes, others believe it helps.

It is well known that obesity and type 2 diabetes in humans are extremely related. It is also known that weight loss in obese or overweight persons tends to reverse the symptoms of diabetes. Then, hoodia is of dual benefit for diabetics, because at one side, it can induce weight loss, and at the other can reduce glucose independently from the appetite suppression effects.

But forget about the personal opinions, and let´s go to the research and development field, where do exist demonstrations about hoodia effectiveness to diabetes.

 

Phytopharm Invention and Diabetes

 

There is one research done, and it is the basis for the USPTO patent # 7033616, assigned to Phytopharm in 2006. Let´s go with some comments about it.

Into the full patent documents, it is stated that "Diabetes is a deficiency condition marked by a habitual discharge of an excessive quantity of urine; in particular, it includes diabetes mellitus, which is a metabolic disorder in which the ability to oxidize carbohydrates is more or less completely lost, usually due to faulty pancreatic activity, especially of the islets of Langerhans, and consequent disturbance of normal insulin mechanism. This produces hyperglycemia with resulting glycosuria and polyuria giving symptoms of thirst, hunger, emaciation and weakness and also imperfect combustion of fats with resulting acidosis, sometimes leading to dyspnea, lipemia, ketonuria, and finally coma; there may also be pruritus and lowered resistance to pyogenic infections (Dorland's Medical Dictionary--24.sup.th Edition--W.B.Saunders Company). "

"The diabetic disease state is characterized by an impaired glucose metabolism that manifests itself in, inter alia, elevated glucose levels in patients suffering therefrom. Generally, diabetes is classified into two distinct subgroups:

Type 1 diabetes

, or insulin-dependent diabetes mellitus (IDDM), which arises when patients lack .beta.-cells producing insulin in their pancreatic glands, and

Type 2 diabetes

, or non-insulin dependent diabetes mellitus (NIDDM), which occurs in patients with, inter alia, impaired .beta.-cell function. "

"At present, Type 1 diabetic patients are treated with insulin, while the majority of Type 2 diabetic patients are treated with hypoglycemic agents, such as sulfonylureas that stimulate .beta.-cell function, with other agents that enhance the tissue selectivity of the patients towards insulin, or with insulin itself.

 

Unfortunately, the use of insulin currently requires multiple daily doses, normally administered by self-injection, with determination of the proper dosage of insulin requiring frequent estimations of the sugar in urine or blood, performed either by the patient or the administering physician. The unintended administration of an excess dose of insulin can result in hypoglycemia, with adverse effects ranging from mild abnormalities in blood glucose to coma, or even death.

Although hypoglycemic agents such as sulfonylureas have been employed widely in the treatment of NIDDM, this treatment is, in many instances, not completely satisfactory. Where existing treatments prove ineffective in normalizing blood sugar levels of patients, there is an increased risk of acquiring diabetic complications.

Also, many patients gradually lose the ability to respond to treatment with sulfonylureas and are thus gradually forced into insulin treatment. Since many extant forms of diabetic therapy have proven ineffective achieving satisfactory glycemic control, there continues to be a great demand for novel therapeutic approaches."

Hoodia and Diabetes

 

The invention in Patent 7033616 relates to a new use for steroidal glycosides and compositions containing them for use in the prevention and treatment of diabetes. The invention relates inter alia to pharmaceutical compositions containing an extract obtainable from a plant of the genus Trichocaulon or Hoodia having anti-diabetic activity; and to the use of such extracts and to compound defined into the patent application and its analogues for the manufacture of medicaments having anti-diabetic activity.

In a particular application, the invention relates to an anti-diabetic agent, to an anti-diabetic composition containing the anti-diabetic agent, and to a method for treating diabetes.

According to such invention, it has been found that the extracts from a plant of the genus Trichocaulon or of the genus Hoodia, the compound of a general formula, as well as the steroidal glycosides derivatives of various other general formula have anti-diabetic activity.

Type 2 Diabetes

The invention is particularly concerned with the treatment of Type II diabetes and the corresponding anti-diabetic agents. The invention provides a new use for steroidal glycosides and compositions containing them for use in the prevention and treatment of diabetes.

The invention provides an anti-diabetic agent, an anti-diabetic composition containing the anti-diabetic agent, a foodstuff or beverage containing the anti-diabetic agent, kits based on the anti-diabetic agent, a method for preventing or treating diabetes or impaired glucose tolerance, and a method of decreasing blood glucose level. The anti-diabetic agent may be an extract from a plant of the genus Trichocaulon or of the genus Hoodia, a compound of general formula, as well as the steroidal glycosides derivatives of of other general formula described into the full document of the patent.

This research demonstrates the positive hoodia effects on diabetics.

Anyway, always consult your doctor before to take hoodia.